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Staff in the Joint Department of Cell and Molecular Biology/Health Sciences and the Institute for the Biotechnology of Infectious Disease [IBID] have interests in the following research areas from which Honours projects may be available in 2006. MSc and PhD projects (full or part-time) are also available in similar areas.
MOLECULAR MEDICINE
Prof A. Simpson
Gene therapy for diabetes: molecular and biochemical study of glucose-responsive insulin secretion from engineered liver cells
Dr B. O'Brien
Identification of the genes that cause autoimmune disease
The role of macrophages in the development of diabetes
Dr B. O'Brien, Dr N. Nassif
Identification of single nucleotide polymorphisms (SNPs) in genes that predispose to disease
Assoc Prof A. Piper
Multidrug resistance and cancer: Regulation of MDR1 transcription in cancers of different origin
Dr N. Nassif
Tumour suppressor gene alterations in colon cancer
Assoc Prof M. Davey
Thiol metabolism in drug resistant leukaemia cells
Dr A. George
Structure and function of P-glycoprotein and other ABC transporters
Prof R. Raison
Engineering therapeutic monoclonal antibodies
FORENSIC BIOLOGY
Assoc Prof A. Piper, Mr S. Walsh
Investigating forensically informative non-autosomal SNP loci
Molecular approaches for ageing bloodstains
Mr S. Walsh, Dr P. Gunn (NSW Police Forensic Services Group), Assoc Prof A. Piper
Understanding Y-STR population genetics for forensic DNA evidence interpretation
Developing a rapid, portable forensic DNA profiling platform for use in the NSW Police Mobile Incident Response Vehicle (MIRV)
Mr S. Walsh, Dr P.Doble (CMF), Agilent Technologies
DNA identification using chip-based capillary electrophoresis technology
Dr T. Sztynda, Dr M. Sutisno (Skullforensics)
Matching ear print details with images for the purposes of human identification
HAEMATOLOGY / PATHOLOGY / BIOTECHNOLOGY
Ms N. Woodland, Dr C. Jackson, Dr N. Le
The role of exogenous osteopontin on the expression of matrix metalloproteinase 2 and 9 inflammatory synoviocytes of the tendon
Dr R. Shepherd, Prof R. Flowers (RNSH)
Australian native nutraceuticals
Dr R. Shepherd
Characterisation of a starch modifying transglycosylase
Antiviral properties of glycans and proteoglycans
MICROBIOLOGY
Prof J. Ellis
Mechanisms of host resistance to parasitic organisms such as Neospora caninum
Prof J. Ellis, D. Stark (St Vincent's Hospital)
Molecular methods for identifying gut parasites of humans
Molecular methods for real time PCR for diagnosis of LGV
Prof J. Ellis, T. Borody (Centre for Digestive Diseases)
Role of parasites in irritable bowel syndrome
Dr A. George
Multidrug resistance in bacteria
Bacteriocin and melanin in Aeromonas media
Dr P. Hansen
Staphylococcus aureas: diversity and host interactions
Prof A. Simpson, Dr R. Hill (CSIRO)
Ecdysone receptors as molecular targets for the development of environmentally-friendly insecticides
Dr F. Torpy
The arbuscular mycorrhizal fungi/acacia symbiosis
Dr F. Torpy, J. Lategan
A novel antimicrobial inhibitory substance produced by Aeromonas media
Dr F. Torpy, Dr J. Tarran (DES)
Bacterial biodegradation of volatile organic air pollutants
HEALTH SCIENCES
Assoc Prof G. Nicholson
Characterisation of arachnid neurotoxins as potential insecticide lead compounds
Determining novel insecticide targets using peptide neurotoxins
Determining actions of sea anemone neurotoxins on voltage-gated ion channels
Assoc Prof G. Nicholson, Dr A. Graudins (UNSW), Assoc Prof K. Broady
Isolation and characterisation of presynaptic neurotoxins from the common death adder
Assoc Prof D. Martin
Physiology of the retinal microvasculature in diabetic retinopathy
Nanobiotechnology of biosensors based on biomimetic lipids
Physiology and biophysics of ion channels
Dr S. Lal, J. Wyndham
EEG and emotion
Dr S. Lal
Driver fatigue
Influence of mobile phone use on brain activity
Dr D. van Reyk, Dr M. Davies (Heart Research)
Modifications of lipoproteins in diabetes and treatment of diabetes-associated Atherosclerosis
Ms J. Wyndham, B. Choy (Maths Sci)
Epidemiology of diabetes
INSTITUTE FOR THE BIOTECHNOLOGY OF INFECTIOUS DISEASE [IBID]
Prof R. Raison, Assoc Prof K. Broady, Dr M. Villavedra
Characterisation of antigen of Neoparamoeba pemaquidensis, the causative agent of AGD [amoebic gill disease] in fish
System versus mucosal immunity in fish
Assoc Prof K. Broady
A molecular biology/proteomic investigation of tick salivary proteins
Dr N. Beebe
Genetic studies on malaria transmitting mosquitoes
Assoc Prof N. Smith, Dr N. Boulter
Determination of the molecular basis for parasite virulence
Immunomodulation of cytokine responses by parasites
Dr S. Belli, Prof M. Wallach, Assoc Prof N. Smith
Molecular characterisation of parasite antigens that are vaccine candidates
Molecular basis for cell growth and differentiation in parasites
Assoc Prof L. Harry
Identification of new antibacterial targets: a proteomic approach
Bacterial cell division and its regulation
Assoc Prof M. Davey
Thiol gene expression in a model nematode
Interested students should contact the appropriate staff member or contact Dr P. Hansen, Coordinator
email: peter.hansen@uts.edu.au
2006 Honours Research Projects pdf version
Honours Application Form
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